Buy MOTS-c Peptide for metabolic and mitochondrial function research in areas such as cellular energy regulation, exercise adaptation, insulin sensitivity, and healthy aging. It is studied for its potential influence on glucose metabolism, insulin sensitivity, skeletal muscle function, and cellular responses to metabolic stress. Nuway Peptides supplies high-purity MOTS-c peptide synthesized in adherence to strict ISO 9001 standards and third-party tested to ensure over 99.9% purity. Same-day shipping available. Sold for research use only.
Key Features
- Research-grade MOTS-c peptide exceeding 99% purity
- Third-party tested by accredited labs through HPLC and mass spectrometry
- Certificate of Analysis (COA) available
- SPPS synthesis methods under ISO 9001 quality standards
- Fast U.S. shipping with same-day processing on qualifying orders
What Is MOTS-c?
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a naturally occurring 16-amino-acid peptide encoded within mitochondrial DNA. First identified in 2015, it belongs to a class of signaling molecules known as mitochondrial-derived peptides (MDPs), which play important roles in cellular metabolism and adaptive stress responses.
Researchers have studied MOTS-c for its potential interactions with pathways involved in glucose utilization, fatty acid metabolism, insulin sensitivity, and cellular energy production. One of its most unique characteristics is its ability to move from the mitochondria to the nucleus during periods of metabolic stress, where it may influence the expression of genes associated with cellular adaptation and survival.
These distinctive properties have established MOTS-c as a prominent subject of investigation in metabolic health, exercise physiology, mitochondrial function, and longevity-related research.
MOTS-c Specifications
| Specification | Value |
| Name and Synonyms | MOTS-c, UNII-A5CV6JFB78, MOTS-c (human) (trifluoroacetate salt) |
| Peptide Type | Mitochondrial-Derived Peptide (MDP) |
| Amino Acid Length | 16 Amino Acids |
| Molecular Formula | C101H152N28O22S2* |
| Molecular Weight | 2174.6 g/mol* |
| PubChem CID | 146675088 |
| CAS Number | 1627580-64-6* |
| Form and Appearance | White to off-white lyophilized powder |
*Specifications may vary depending on formulation, salt form, or manufacturing batch. Refer to the batch-specific Certificate of Analysis (COA) for current analytical data.
Research Applications
Researchers frequently investigate MOTS-c across several areas of metabolic and longevity science, including cellular energy regulation, exercise physiology, insulin sensitivity, body composition, and healthy aging.
Metabolic Function and Energy Regulation
MOTS-c is frequently studied for its role in metabolic homeostasis and cellular energy management [1]. Researchers have investigated how the peptide influences glucose utilization, nutrient sensing, and metabolic efficiency under both normal and stressed conditions.
Insulin Sensitivity Research
One of the most extensively studied aspects of MOTS-c involves its relationship with insulin sensitivity and glucose metabolism. Scientific investigations have explored how the peptide interacts with skeletal muscle and metabolic signaling pathways associated with glucose uptake and energy utilization [1].
Exercise Performance and Skeletal Muscle Biology
Researchers have examined MOTS-c for its potential role in exercise adaptation, physical performance, and skeletal muscle metabolism. Studies suggest the peptide may influence pathways involved in energy production and the body’s response to physical exertion [2].
Fat Metabolism and Body Composition Research
MOTS-c has attracted significant interest in studies focused on fat utilization and metabolic flexibility. Research continues to explore how the peptide may influence fatty acid oxidation and broader metabolic pathways associated with energy expenditure [3].
Longevity and Healthy Aging Research
As a mitochondrial-derived signaling peptide, MOTS-c is frequently included in research involving aging, cellular resilience, and long-term metabolic health. Scientists continue to investigate its role in adaptive stress responses and age-related biological processes.
Why Buy MOTS-c From Nuway Peptides?
At Nuway Peptides, every product is manufactured and tested according to strict quality standards to help ensure dependable results in laboratory settings. Our MOTS-c peptide for sale is designed to support the needs of individual researchers as well as scientific institutions, right from synthesis stage and analytical verification to packaging and shipment. Ultra-pure and rigorously stable, buy research compounds from NuWay for reliable and consistent results.
99%+ Purity with Independent Testing
Every batch of MOTS-c undergoes third-party analytical verification to confirm identity, purity, and consistency. Advanced testing methods, including High-Performance Liquid Chromatography (HPLC) and mass spectrometry, help ensure researchers receive a product that meets stringent quality requirements. Certificates of Analysis (COAs) are available for additional transparency and confidence.
Manufactured to Strict Quality Standards
Nuway Peptides partners with manufacturing facilities operating under ISO 9001 quality-management standards and utilizes established solid-phase peptide synthesis (SPPS) methods. These processes help maintain consistency from batch to batch while supporting the production of high-purity research peptides suitable for advanced scientific applications.
Reliable U.S. Peptide Supplier
Nuway Peptides is committed to providing a dependable experience for researchers across the United States. Orders are processed quickly, securely packaged, and shipped through trusted carriers to help ensure products arrive in optimal condition. Orders placed before 1 PM EST qualify for same-day shipping, helping researchers avoid unnecessary delays in their work.
Disclaimer: Research Use Only
MOTS-c is a research-grade peptide supplied exclusively for laboratory and scientific research purposes. It is not intended for human or veterinary use, consumption, or administration.
Scientific References
References
1. Zheng, Y., Wei, Z., & Wang, T. (2023). MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation. Frontiers in Endocrinology, 14, 1120533. https://www.frontiersin.org/articles/10.3389/fendo.2023.1120533/full
2. Hyatt, J. K. (2022). MOTS-c increases in skeletal muscle following long-term physical activity and improves acute exercise performance after a single dose. Physiological Reports, 10(13), e15377. https://physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15377
3. Gao, Y., Wei, X., Wei, P., Lu, H., Zhong, L., Tan, J., Liu, H., & Liu, Z. (2023). MOTS-c functionally prevents metabolic disorders. Metabolites, 13(1), 125. https://www.mdpi.com/2218-1989/13/1/125
